MCSE is a Microsoft IT certification. It used to stand for Microsoft Certified Systems Engineer (MCSE), but Microsoft has since updated the certification to maintain its relevance in today's market where IT infrastructure and services are increasingly being put into the cloud. MCSE now stands for Microsoft Certified Solutions Expert and now covers on-premise and cloud-based IT solutions.
MCSE is a recognized and respected IT industry certification that has been around for 20 years. It now covers a broader set of technologies at a deeper level and places a lot of emphasis on cutting-edge technologies, all of which will be biased toward Microsoft software.
CCNA is a Cisco Systems IT certification. It stands for Cisco Certified Network Associate (CCNA). It is a networking qualification that validates your ability to install, configure and troubleshoot medium-sized switched and routed networks, connecting to remote sites using WAN technologies.
CCNA is a highly regarded IT networking certification which is also a stepping-stone to more advanced Cisco certifications like the CCNP (Cisco Certified Network Professional) and CCIE (Cisco Certified Network Expert).
Read more about the CCNA certification.